Research Awards

Since 1964, The Kidney Foundation of Canada has played a fundamental role in supporting and advancing kidney-related research in Canada. In fact, The Kidney Foundation of Canada funds over one third of all kidney-related research in Canada and by the end of 2013, the Foundation’s total commitment to research will have exceeded $110 million.

Research brings hope to patients and their families for better treatment options and a better quality of life. It is thanks to the tireless efforts and the commitment of thousands of dedicated volunteers and contributors across the country that this important research is possible.

The Kidney Foundation of Canada is proud of the role it has played over the past four decades and recognizes that the continual enhancement of research capacity is critical to the advancement of knowledge and the career development and retention of renal researchers.

For 2013-2014, The Kidney Foundation of Canada is once again upholding its commitment to supporting research excellence through Research Grants, Fellowships and Scholarships awarded to investigators from all scientific disciplines.

KFOC 2013-2014 Research Awards

RECIPIENT

INSTITUTION

TITLE OF RESEARCH

CATEGORY

PROGRAM/AMOUNT FUNDED

Advani, Andrew

St. Michael's Hospital,
Toronto

Histone methyltransferases in diabetic nephropathy

Diabetes

Biomedical Research Grant
2012 - 2014
$ 100,000

Alexander, Todd

University of Alberta,
Edmonton

Molecules & mechanisms mediating proximal tubular calcium flux

Water, Salt and Calcium handling by the Kidney

Biomedical Research Grant
2011 - 2014
$ 150,000

Bouchard, Maxime

McGill University,
Montreal

Mouse models of urogenital developmental diseases

Kidney Development

Biomedical Research Grant
2012 - 2014
$ 100,000

Bridgewater, Darren

McMaster University,
Hamilton

Causes and cures for congenital kidney disease: a role for β-catenin

Kidney Development

Biomedical Research Grant
2012 - 2014
$ 99,982

Brimble, Kenneth

St. Joseph's Healthcare Hamilton

Impact of cholecalciferol supplementation on LV mass in peritoneal dialysis patients: a randomized controlled trial

Dialysis

Biomedical Research Grant
2012 - 2014
$ 59,630

Cailhier, Jean-François

CRCHUM - Hôpital Notre-Dame,
Montreal

Macrophage reprogramming by the microenvironment: evaluation of the role of MFG-E8 and its signaling pathways in renal fibrosis

Renal Failure

Biomedical Research Grant
2012 - 2014
$ 100,000

Chan, John

CRCHUM - Hôtel-Dieu,
Montreal

Role(s) of intrarenal angiotensin-converting enzyme-2 in hypertension and nephropathy development in diabetic mice

Diabetes

Biomedical Research Grant
2012 - 2014
$ 100,000

Cherney, David
Bruce Perkins

University Health Network,
Toronto

A deep phenotyping approach to assess the effect of uric acid lowering in patients with uncomplicated type 1 diabetes mellitus

Diabetes

Biomedical Research Grant
2013 – 2015
$ 12,323

Chraibi, Ahmed

Université de Sherbrooke,
Sherbrooke

Rôle périphérique de l'apéline dans le maintien de l'équilibre hydrosodique: effets sur l'activité et l'expression du canal sodique épithélial, de la Na,K-ATPase et des aquaporines au niveau rénal

Water, Salt and Calcium handling by the Kidney

Biomedical Research Grant
2012 - 2014
$ 100,000

Clase, Catherine
Azim S. Gangji, Eleanor M. Pullenayegum

McMaster University,
Hamilton

Bioimpedance as a predictor of cardiovascular outcomes in patients with chronic kidney disease

Renal Failure

Biomedical Research Grant
2012 - 2014
$ 100,000

Cordat, Emmanuelle

University of Alberta,
Edmonton

Acid-base homeostasis, distal renal tubular acidosis and bicarbonate transporters

Water, Salt and Calcium handling by the Kidney

Biomedical Research Grant
2012 - 2014
$ 100,000

Côté, Josée
Marie-Josée Hébert, Marie-Chantal Fortin, Sylvie Dubois, Géraldine Martorella

CRCHUM - Hôpital Notre-Dame,
Montreal

Évaluation d'une intervention virtuelle, TRANSPLANT-TAVIE, visant à optimiser l'adhésion aux médicaments antirejet chez les personnes greffées

Transplantation

Allied Health Research Grant
2013 - 2015
$ 98,320

De Serres, Sacha

Université Laval,
Quebec

Assessment of the role of circulating monocytes in the development of chronic allograft damage in kidney transplant recipients

Transplantation

Biomedical Research Grant
2012 - 2014
$ 100,000

De Serres, Sacha

Université Laval,
Quebec

Assessment of the role of circulating monicytes in the development of chronic allograft damage in kidney transplant recipients

Transplantation

Krescent New Investigator Award
2012 - 2015
$ 210,000

Co-funded by CIHR, CSN, FRQS
and KFOC

Du, Caigan
Gerald Da Roza, Jayachandran N Kizhakkedathu, Asher  Mendelson

University of British Columbia,
Vancouver

Metabolic benefits of novel glucose-sparing peritoneal dialysis solutions in diabetics

Dialysis

Biomedical Research Grant
2013 - 2015
$ 100,000

Farragher, Janine
Supervisors: Helene Polatajko, Sarbjit Vanita Jassal

University Health Network,
Toronto

Arm and hand function after arteriovenous access creation for chronic maintenance hemodialysis

Dialysis

Allied Health Doctoral Fellowship
2013 - 2015
$ 50,000

Fortin, Marie-Chantal

CRCHUM - Hôpital Notre-Dame,
Montreal

A qualitative study on transplantation stakeholders’ views on ethical issues related to the participation
of compatible pairs in kidney exchange programs, and a proposal for guidelines

Transplantation

Krescent New Investigator Award
2011 - 2014
$ 210,000

Co-funded by CIHR, CSN, FRQS
and KFOC

Garg, Amit
Blayne K. Welk, Danielle Nash, Sonia Thomas, Ngan Lam

Lawson Health Research Institute - SJH,
London

Long-term risks of kidney stones requiring interventionand bleeding requiring hospitalization in living kidney donors

Organ Donation

Biomedical Research Grant
2013 - 2014
$ 49,112

Gilbert, Richard
Michael McBurney, Yanling Zhang

St. Michael's Hospital,
Toronto

The role of sirtuin 1 in chronic kidney disease

Glomerulonephritis

Biomedical Research Grant
2012 - 2014
$ 93,941

Gommerman, Jennifer

University of Toronto,
Toronto

Exploring the link between IgA nephropathy and the mucosal immune system

Glomerulonephritis

Biomedical Research Grant
2012 - 2014
$ 100,000

Gross, Oliver

University Medical Centre Goettingen,
Germany

Nephroprotective and antifibrotic potential of Micro-RNA21 in the COL4A3 mouse model of Alport syndrome

Kidney Biology

Alport Syndrome Research Grant
2013 – 2014
$ 100,000

Co-funded by the ASF, Macquarie Group Foundation, Pedersen Family and KFOC

Gunaratnam, Lakshman

Western University,
London

Exploiting KIM-1 signalling to ameliorate renal ischemia reperfusion injury through clearance of apoptotic cells

Acute Renal Failure

Krescent New Investigator Award
2011 - 2014
$ 210,000

Co-funded by CIHR, CSN and KFOC

Gupta, Indra
Aimee K. Ryan

McGill University Health Centre,
Montreal

Claudin function in kidney development and in disease

Kidney Development

Biomedical Research Grant
2013 - 2015
$ 100,000

Hartwig, Sunny

University of Prince Edward Island,
Charlottetown

Definin the role of Sox4 and Sox11 during kidney development

Kidney Development

Biomedical Research Grant
2013 – 2015
$ 100,000

Hébert, Marie-Josée

CRCHUM - Hôpital Notre-Dame,
Montreal

Anti-LG3 antibodies: novel biomarkers and effectors of vascular rejection

Renal Failure

Biomedical Research Grant
2013 - 2015
$ 100,000

Hébert, Richard

University of Ottawa

The role of PGE2/EP3 receptors in diabetic mouse kidney

Diabetes

Biomedical Research Grant
2012 - 2014
$ 100,000

Ho, Juliet
John Wilkins

University of Manitoba,
Winnipeg

Novel biomakers of acute kidney injury

Renal Failure

Biomedical Research Grant
2012 - 2015
$ 150,000

Ho, Juliet

University of Manitoba,
Winnipeg

Novel urine biomarkers of progressive interstitial fibrosis/tubular atrophy and renal allograft dysfunction & loss

Renal Failure

Krescent New Investigator Award
2011 - 2014
$ 210,000

Co-funded by CIHR, CSN and KFOC

Hunter, Graeme
Harvey Alan Goldberg, Mikko Karttunen

Western University,
London

Inhibition of calcium oxalate crystallization by osteopontin

Water, Salt and Calcium handling by the Kidney

Biomedical Research Grant
2013 - 2015
$ 99,756

Isenring, Paul

Université Laval,
Quebec

Molecular characterization of renal K-C1 cotransporters

Water, Salt and Calcium handling by the Kidney

Biomedical Research Grant
2013 - 2015
$ 100,000

James, Matthew

University of Calgary,
Calgary

Processes of care and clinical outcomes of acute kidney injury: a multidisiplinary research program

Acute Renal Failure

Krescent New Investigator Award
2012 - 2015
$ 210,000

Co-funded by CIHR, CSN and KFOC

Jensen, Victor L.
Supervisor: Michel R. Leroux

Simon Fraser University,
Burnaby

Ciliary transition zone structure and function

Genetics

Krescent Post Doctoral Fellowship
2013 – 2016
$ 165,000

Co-funded by CIHR, CSN, KFOC and Simon Fraser University

Jewett, Michael
Jennifer Michelle Jones, Lori Wood, Martin Neil Reaume, Jennifer Jane Knox

University Health Network,
Toronto

Kidney Cancer Research Network of Canada

Cancer

Kidney Disease – Research Chair
2012 - 2015
$ 600,000

Co-funded by CIHR, KCC and KFOC

Kapus, Andras

St. Michael's Hospital,
Toronto

Pericyte, a new culprit in renal fibrosis: a cell biology approach

Kidney Biology

Biomedical Research Grant
2013 - 2015
$ 100,000

Kennedy, Christopher
Douglas Gray

Ottawa Hospital Research Institute

Alpha-actinin-4 associated FSGS: a role for ubiquitin C-terninal hydrolase-1 (UCH-L1)

Kidney Biology

Biomedical Research Grant
2013 - 2015
$ 100,000

The Pearson Family Research Award

Korus, Moira
Jennifer Stinson, Cameron Ross Hetherington, Ian  Chen, Anna F. Gold

The Hospital for Sick Children, Research Institute,
Toronto

Teen taking charge: managing my transplant online

Transplantation

Allied Health Research Grant
2012 - 2014
$ 99,900

Lafrance, Jean-Philippe
Martine Leblanc, Elham Rahme, Annie-Claude Labbé

Maisonneuve-Rosemont Hospital,
Montreal

Physical space factors of hemodialysis facilities and risk of access-related infections and infection-related hospitalizations among incident chronic dialysis patients

Dialysis

Biomedical Research Grant
2013 - 2015
$ 100,000

Lam, Ngan
Supervisor: Amit Garg

Lawson Health Research Institute - SJH,
London

Risk of acute kidney injury in patients receiving antiviral drugs for herpes infection

Acute Renal Failure

Krescent Post Doctoral Fellowship
2012 - 2015
$ 195,000

Co-funded by CIHR, CSN and KFOC

Lapointe, Jean-Yves

Université de Montreal

Functional and molecular regulation of proximal tubule contransport mechanisms

Kidney Biology

Biomedical Research Grant
2012 – 2014
$ 100,000

Lapointe, Réjean

CRCHUM - Hôpital Notre-Dame,
Montreal

Immunological signature linked to clinical outcome in kidney cancer patients: correlation with normal individuals and uremic/transplanted patients

Cancer

Biomedical Research Grant
2013 - 2015
$ 100,000

Lemay, Serge

McGill University,
Montreal

Impact and mechanisms of tyrosine kinase inhibitory signaling in renal ischemia/reperfusion injury

Kidney Biology

Biomedical Research Grant
2012 - 2014
$ 100,000

Li, Alvin
Supervisor: Amit Garg

Western University,
London

Increasing organ and tissue donor registration: a systematic review of interventions and socio-demographic determinants of registration

Organ Donation

Allied Health Doctoral Fellowship
2013 - 2014
$ 24,167

Lok, Charmaine
Amiram Gafni, Louise M. Moist, Andrew Alfred House, Lehana Thabane

University Health Network,
Toronto

Hemodialysis infection prevention with polysporin triple ointment versus shower technique in satellite centres (HIPPOS-SAT)

Dialysis

Biomedical Research Grant
2012 - 2014
$ 95,023

Mager, Diana
Peter A Senior, Joline Vretenar, Stephanie Schwindt

University of Alberta,
Edmonton

Vitamin D supplementation and bone health in adults with diabetic nephropathy

Diabetes

Allied Health Research Grant
2012 - 2014
$ 99,990

Margetts, Peter

McMaster University,
Hamilton

Peritoneal fibrosis and epithelial mesenchymal transition

Dialysis

Biomedical Research Grant
2013 - 2015
$ 100,000

Medin, Jeffrey
Aneal A. Khan, Michael L. West, Christiane Auray-Blais, Robin E. Casey, Joe T. R. Clarke

University Health Network,
Toronto

The FACTs Project: Fabry disease clinical research and therapeutics

Genetics

Emerging Team Grant: Rare Diseases
2011 - 2017
$ 1,603,333

Co-funded by CIHR

Molnar, Amber
Supervisors: Gregory A. Knoll, Carl van Walraven

Ottawa Hospital Research Institute

The impact of acute kidney injury on the risk of death or graft loss in the renal transplant population

Acute Kidney Injury

Krescent Post Doctoral Fellowship
2013 - 2015
$ 130,000

Co-funded by CIHR, CSN, KFOC and Ottawa Hospital Research Institute

Muruve, Daniel

University of Calgary,
Calgary

NOD-Like receptors and inflammasomes in kidney disease

Kidney Biology

Biomedical Research Grant
2013 – 2015
$ 50,000

Nguan, Christopher
Paul A. Keown, Martin E. Gleave

University of British Columbia,
Vancouver

Research and development of novel medical technology to repair and prevent kidney injury

Transplantation

Biomedical Research Grant
2012 - 2014
$ 100,000

Pauly, Robert

University of Alberta,
Edmonton

Predicting mortality, technique survival and training failure for a Canadian multicentre home hemodialysis cohort

Dialysis

Biomedical Research Grant
2011 - 2014
$ 143,016

Pause, Arnim
Marie-Claude Gingras

McGill University,
Montreal

Investigation of VHL and p53 cooperation in HIF activation, metabolism and tumorigenesis

Cancer

Biomedical Research Grant
2013 - 2015
$ 100,000

Pei, York

University Health Network
Toronto

Molecular genetcs of idiopathic nephrotic syndrome

Genetics

Biomedical Research Grant

2012 – 2014
$ 100,000

Cofunded by The NephCure Foundation and KFOC

Reich, Heather
David Guttman, Rulan S. Parekh, Michelle A. Hladunewich, Jan  Novak

University Health Network,
Toronto

Alteration of the microbiome in IgA nephropathy

Glomerulonephritis

Biomedical Research Grant
2013 - 2015
$ 100,000

The Pearson Family Research Award


Rose, Caren
Supervisor(s): John Gill, Charlyn Black

University of British Columbia
Vancouver

Estimating the number of individuals who die in hospital and are candidates for deceased organ donation

Organ Donation

Krescent Allied Health Doctoral Award
2010 – 2013
$40,000


Co-funded by CIHR, CSN and KFOC

Rosenblum, Norman

The Hospital for Sick Children, Research Institute,
Toronto

Control of renal branching morphogenesis by Hedgehog-GLI3 signaling

Kidney Biology

Biomedical Research Grant
2012 - 2014
$ 100,000

Samuel, Susan

University of Calgary,
Calgary

A health services research program in pediatric nephrology

Glomerulonephritis

Krescent New Investigator
2011 – 2014
$210,000

Co-funded by CCHCSP, CIHR, CSN, KFOC and University of Calgary

Savige, Judith
Ricardo, Sharon

The University of Melbourne,
Melbourne, Australia

Derivation and characterisation of induced pluripotent stem cell lines from patients with X-linked Alport Syndrome - a model for examining mechanisms and therapies

Kidney Biology

Alport Syndrome Research Grant
2013 – 2014
$ 100,000

Co-funded by the ASF, the Macquarie Group Foundation, Pedersen Family and KFOC

Schick Makaroff, Kara
Supervisor: Anita E. Molzahn

University of Alberta,
Edmonton

Health-related quality of life assessment in clinical nephrology nursing practice

Quality of Life

Krescent Post Doctoral Fellowship
2011 - 2014
$ 165,000

Co-funded by CIHR, CSN and KFOC

Scholey, James

University of Toronto,
Toronto

Adiponectin signaling and angiotensin-II induced kidney injury

Renal Failure

Biomedical Research Grant
2013 - 2015
$ 100,000

Szaszi, Katalin

St. Michael's Hospital,
Toronto

Tumor necrosis factor-a-inducedactivation of the EGF receptor in tubular epithelium: mechanisms and role in junction regulation

Kidney Biology

Biomedical Research Grant
2012 - 2014
$ 100,000

Tangri, Navdeep

University of Manitoba,
Winnipeg

Outcomes in chronic kidney disease

Chronic Kidney Disease

Krescent Infrastructure Support
2013 - 2014
$ 25,000

Tangri, Navdeep

University of Manitoba,
Winnipeg

Outcomes in chronic kidney disease

Chronic Kidney Disease

Krescent New Investigator Award
2013 - 2016
$ 210,000

Co-funded by CIHR, CSN, KFOC and University of Manitoba

Tonelli, Marcello Antonio

University of Alberta
Edmonton

Examining the impact of using two dialysers in parallel on dialysis adequacy in hemodialysis patients

Renal Failure

Biomedical Research Grant
2013 – 2015
$ 94,766

Torban, Elena

McGill University,
Montreal

Pathogenesis of the recurrent form of focal segmented glomerulosclerosis

Glomerulonephritis

Biomedical Research Grant
2013 - 2015
$ 33,000

Troyanov, Stéphan
François Madore, Philip Awadalla

Hôpital du Sacré-Coeur de Montreal

Uromodulin and the risk of chronic kidney disease in a large Canadian cohort

Genetics

Biomedical Research Grant
2013 - 2015
$ 100,000

Turcotte, Sandra

Université de Moncton,
Moncton

Targeting the loss of the von Hippel-Lindau tumor suppressor gene at a late-stage of autophagy for the development of anticancer therapy

Cancer

Krescent New Investigator Award
2012 - 2015
$ 180,000

Co-funded by CIHR, CSN, KFOC
and NBHRF

Ummel, Deborah
Supervisor: Marie Achille

Université de Montreal

Étude de l'impact d’une donation vivante de rein sur la relation entre le donneur et le receveur

Organ Donation

Allied Health Doctoral Fellowship
2013 - 2015
$ 58,000

Walsh, Michael

McMaster University,
Hamilton

Remote ischemic preconditioning in cardiac surgery trial (Remote IMPACT)

Acute Renal Failure

Krescent New Investigator Award
2011 - 2014
$ 210,000

Co-funded by CIHR, CSN and KFOC

Weir, Matthew
Jessica M Sontrop

Lawson Health Research Institute - SJH,
London

Nano-particle curcumin to prevent progressive chronic kidney disease

Chronic Kidney Disease

Biomedical Research Grant
2013 - 2016
$ 148,044

West, Lori
Timothy A. Caulfield, Marie-Josée Hébert, Atul Humar, Gregory A. Knoll, Megan Levings, Seema Mitel, Denis-Claude Roy, Kirk Schultz, James Shapiro

University of Alberta
Edmonton

The Canadian National Transplant Research Program: Increasing Donation and Improving Transplantation Outcomes

Transplantation

Program Grant in Transplantation Research
2013 – 2018
$ 11,500,000

Co-funded by CIHR and KFOC

Wiebe, Chris
Supervisor: Peter Nickerson

University of Manitoba,
Winnipeg

Correlation of HLA Alloepitopes with the development of de novo donor specific antibodies after renal transplantation

Transplantation

Krescent Post Doctoral Fellowship
2012 - 2014
$ 130,000

Co-funded by CIHR, CSN and KFOC

Yousef, George
John McPherson, Gerald J. Prud'homme

St. Michael's Hospital,
Toronto

miRNAs are involved in the formation and maintenance of a highly aggressive form of kidney cancer cells with stem cell properties and contribute to cancer aggressiveness

Cancer

Biomedical Research Grant
2013 - 2015
$ 99,600

Yuen, Darren

St. Michael's Hospital,
Toronto

The role of Slit2-Robo signalling in early diabetic nephropathy

Diabetes

Biomedical Research Grant
2013 - 2016
$ 148,899

Yuen, Darren

St. Michael's Hospital,
Toronto

Developing novel therapies for fibrovascular injury in the kidney: targeting the actin cytoskeleton

Chronic Kidney Disease

Krescent Infrastructure Support
2013 - 2014
$ 25,000

Yuen, Darren

St. Michael's Hospital,
Toronto

Developing novel therapies for fibrovascular injury in the kidney: targeting the actin cytoskeleton

Chronic Kidney Disease

Krescent New Investigator Award
2013 - 2016
$ 210,000

Co-funded by CDA, CIHR, CSN, KFOC and St. Michael’s Hospital

 

2011-2012 Research Awards Recipients
2010-2011 Research Awards Recipients
2009-2010 Research Awards Recipients
2008-2009 Research Awards Recipients
2007-2008 Research Awards Recipients
2006-2007 Research Awards Recipients



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